Litcius/Paper detail

The mitochondrial calcium uniporter mediates mitochondrial Fe2+ uptake and hepatotoxicity after acetaminophen

Jiangting Hu, Anna‐Liisa Nieminen, James L. Weemhoff, Hartmut Jaeschke, Laura G. Murphy, Judith Dent, John J. Lemasters

2023Toxicology and Applied Pharmacology14 citationsDOIOpen Access PDF

Topics & Concepts

UniporterMitochondrionAcetaminophenHepatocyteMitochondrial permeability transition poreChemistryLiver injuryViability assayPharmacologyBiochemistryProgrammed cell deathMolecular biologyIn vitroApoptosisBiologyCytosolEnzymeDrug-Induced Hepatotoxicity and ProtectionLiver Disease and TransplantationDrug Transport and Resistance Mechanisms