A ROS and shear stress dual-sensitive bionic system with cross-linked dendrimers for atherosclerosis therapy
Meili Shen, Shunyu Yao, Shaojing Li, Xiaodong Wu, Shun Liu, Qingbiao Yang, Jianshi Du, Jingyuan Wang, Xiangyu Zheng, Yapeng Li
Abstract
. Therefore, a biomimetic drug delivery system with dual sensitivity to ROS and shear stress would become a promising strategy for the treatment of atherosclerosis.
Topics & Concepts
In vivoShear stressDrug deliveryDendrimerMaterials scienceBiophysicsDrugChemistryBiomedical engineeringPharmacologyMedicineNanotechnologyBiochemistryBiologyComposite materialBiotechnologyDendrimers and Hyperbranched PolymersRNA Interference and Gene DeliveryProtein Degradation and Inhibitors