Symmetrical di-substituted phenylamino-<i>s</i>-triazine derivatives as anticancer agents: <i>in vitro</i> and <i>in silico</i> approach
Em Canh Pham, Bich-Ngoc Thi Le, Anh T. Ngo, Long Binh Vong, Tuyen Ngoc Truong
Abstract
This study aimed to synthesize symmetrical phenylamino- s -triazine derivatives with one aromatic amine and two hexagonal saturated cyclic amines and evaluate their anticancer activity. The potential derivatives have been investigated in silico .
Topics & Concepts
In silicoTriazineChemistryIn vitroAmine gas treatingCombinatorial chemistryStereochemistryOrganic chemistryBiochemistryGeneSynthesis and Characterization of Heterocyclic CompoundsClick Chemistry and ApplicationsSynthesis and biological activity