Quantifying the influences of radiation therapy on deformability of human red blood cells by dual-beam optical tweezers
Medine Tuna Inanc, İrem Demirkan, Cemile Ceylan, Alper Özkan, Ö. Gündoğdu, Utku Goreke, Umut A. Gürkan, Mehmet Burçin Ünlü
Abstract
= 0.2) dose groups. Based on these findings, we conclude that radiotherapy exposure may alter the deformability of red blood cells depending on the dose amount, and measurement of deformability index by dual-beam optical tweezers can serve as a sensitive biomarker to probe responses of cells to the radiotherapy.
Topics & Concepts
Radiation therapyOptical tweezersIrradiationIn vitroMedicineErythrocyte deformabilityNuclear medicineBiomedical engineeringChemistryBiophysicsRed blood cellInternal medicineOpticsBiologyBiochemistryNuclear physicsPhysicsErythrocyte Function and PathophysiologyBlood properties and coagulationDigital Holography and Microscopy