Metallothionein Alleviates Glutathione Depletion–Induced Oxidative Cardiomyopathy through CISD1-Dependent Regulation of Ferroptosis in Murine Hearts
Fengjuan Li, Shouzhi Fu, Hua Ye, Yihan Hu, Jianxin Chen, Jamie R. Privratsky, Wei Yu, Feng Dong, Rüssel J. Reiter, Maolong Dong, Jun Guo, Jun Ren
Topics & Concepts
MetallothioneinGlutathioneOxidative stressCardiomyopathyOxidative phosphorylationGPX4Oxidative damageBiologyChemistryInternal medicineMedicineEndocrinologyBiochemistryHeart failureGlutathione peroxidaseEnzymeGeneGDF15 and Related BiomarkersTrace Elements in HealthRenin-Angiotensin System Studies