Disulfide radical anion as a super-reductant in biology and photoredox chemistry
Qilei Zhu, Cyrille Costentin, JoAnne Stubbe, Daniel G. Nocera
Abstract
Peak and half-peak potentials poorly approximate standard reduction potentials ( E 0 ), especially for compounds that dissociate upon reduction. We determine E 0 of disulfides and show cysteine disulfide radical anion to be a powerful biological reductant.
Topics & Concepts
ChemistryRibonucleotide reductaseCysteineCleavage (geology)Radical ionIonElectrochemistryCofactorRedoxCombinatorial chemistryNucleotideStereochemistryEnzymeOrganic chemistryBiochemistryElectrodeEngineeringGeotechnical engineeringPhysical chemistryGeneFracture (geology)Protein subunitRadical Photochemical ReactionsCO2 Reduction Techniques and CatalystsMetal-Catalyzed Oxygenation Mechanisms