Genistein exhibits therapeutic potential for PCOS mice <i>via</i> the ER-Nrf2-Foxo1-ROS pathway
Man Luo, Lianwen Zheng, Y Wang, Ji‐Cheng Huang, Zhan‐Qing Yang, Zhan‐Peng Yue, Bin Guo
Abstract
GEN exhibited therapeutic potential for PCOS mice by enhancing the antioxidant capability and preventing the mitochondrial dysfunction dependent on the ER-Nrf2-Foxo1 pathway.
Topics & Concepts
Polycystic ovaryEndocrinologyFOXO1Internal medicineGenisteinBiologyOvaryAntioxidantOxidative stressApoptosisMedicineInsulin resistanceInsulinBiochemistryProtein kinase BReproductive Biology and FertilityOvarian function and disordersEndometriosis Research and Treatment