Interaction of SOX5 with SOX9 promotes warfarin-induced aortic valve interstitial cell calcification by repressing transcriptional activation of LRP6
Ming Qiu, Yan Lu, Junhan Li, Jia Gu, Yue Ji, Yongfeng Shao, Xiangqing Kong, Wei Sun
Topics & Concepts
Gene knockdownChromatin immunoprecipitationCalcificationTranscription factorPAX6ChemistryImmunostainingMolecular biologyCell biologyBiologyCancer researchInternal medicinePromoterGene expressionGeneMedicineImmunohistochemistryImmunologyBiochemistryCardiac Valve Diseases and TreatmentsProtease and Inhibitor MechanismsCalpain Protease Function and Regulation