Microalgae oil from<i>Schizochytrium</i>sp. alleviates obesity and modulates gut microbiota in high-fat diet-fed mice
Liyuan Ran, Jinhui Yu, Rui Ma, Qing Yao, Mingjie Wang, Yuping Bi, Zichao Yu, Yingjie Wu
Abstract
and several pathogens. We also found that SMO recovers the HFD-disturbed metabolic capability of gut microbiota. It can increase the abundance of several metabolism-related pathways, such as those of amino acids, SCFAs and bile acid, and decrease the level of the LPS biosynthesis pathway, which probably contributes to an improvement of lipid metabolism and restoration of the colonic mucosal barrier impaired by HFD. Our data suggest that SMO can be used as a superior dietary supplement for alleviating obesity.
Topics & Concepts
Gut floraFood scienceObesityBiologyWestern dietBiochemistryEndocrinologyGut microbiota and healthDiet and metabolism studiesDietary Effects on Health