Punicalagin as an allosteric NSP13 helicase inhibitor potently suppresses SARS-CoV-2 replication in vitro
Lian Lu, Yun Peng, Huiqiao Yao, Yanqun Wang, Jinyu Li, Yang Yang, Zhonghui Lin
Topics & Concepts
HelicaseAllosteric regulationVero cellChemistryCoronavirusDocking (animal)In vitroBiochemistryBiologyVirologyEnzymeCoronavirus disease 2019 (COVID-19)MedicineGeneInfectious disease (medical specialty)RNANursingPathologyDiseaseNanoparticles: synthesis and applicationsPomegranate: compositions and health benefitsPhytochemicals and Medicinal Plants