Endoplasmic reticulum-targeted iridium(III) photosensitizer induces pyroptosis for augmented tumor immunotherapy
Yun-Shi Zhi, Tie Chen, Bin-Fa Liang, Shan Jiang, Dahong Yao, Zhendan He, Chenyang Li, Liang He, Zhengyin Pan
Topics & Concepts
Immunogenic cell deathChemistryCancer researchPhotosensitizerTumor microenvironmentImmunotherapyCalreticulinPhotodynamic therapyEndoplasmic reticulumImmune systemPyroptosisProgrammed cell deathApoptosisImmunologyMedicineBiochemistryTumor cellsOrganic chemistryInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideEndoplasmic Reticulum Stress and Disease