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Utilization of the repeated squat-stand model for studying the directional sensitivity of the cerebral pressure-flow relationship

Lawrence Labrecque, Jonathan D. Smirl, Patrice Brassard

2021Journal of Applied Physiology36 citationsDOI

Abstract

Repeated squat-stand maneuvers are able to examine the directional sensitivity of the cerebral pressure-flow relationship. These maneuvers induce stable physiological cyclic changes where brain blood flow changes with blood pressure increases are buffered more than blood pressure decreases. These results highlight the importance of considering directional blood pressure changes within cerebral autoregulation.

Topics & Concepts

AutoregulationCerebral blood flowSquatCerebral autoregulationBlood pressureBlood flowSensitivity (control systems)CardiologyAnesthesiaMedicineInternal medicinePhysical medicine and rehabilitationEngineeringElectronic engineeringTraumatic Brain Injury and Neurovascular DisturbancesOptical Imaging and Spectroscopy TechniquesCerebrospinal fluid and hydrocephalus
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