New aromatic hydrazones: Synthesis, structural analysis, DFT study, biological activity, ADME-T properties and in silico evaluation of their inhibition of SAS-CoV-2 main protease
Lilia Adjissi, Nadjib Chafai, Khalissa Benbouguerra, Imene Kirouani, Abdelkader Hellal, Houdheifa Layaida, Meriem Elkolli, Chawki Bensouıcı, Salah Chafaa
Topics & Concepts
ChemistryADMEDensity functional theoryHydrazine (antidepressant)Carbon-13 NMRMoleculeABTSCombinatorial chemistryDPPHProton NMRComputational chemistryAntibacterial activityAutoDockOrganic chemistryIn silicoStereochemistryAntioxidantChromatographyBiologyBacteriaIn vitroGeneticsBiochemistryGeneSynthesis and biological activityNonlinear Optical Materials ResearchSynthesis and Characterization of Heterocyclic Compounds