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A lower X-gate in TASK channels traps inhibitors within the vestibule

Karin E. J. Rödström, Aytuğ K. Kiper, Wei Zhang, Susanne Rinné, A.C.W. Pike, Matthias Goldstein, Linus J. Conrad, Martina Delbeck, Michael G. Hahn, Heinrich Meier, Magdalena Platzk, Andrew Quigley, David Speedman, Leela Shrestha, Shubhashish Mukhopadhyay, N. Burgess-Brown, Stephen J. Tucker, Thomas Müller, Niels Decher, Elisabeth P. Carpenter

2020Nature105 citationsDOI

Topics & Concepts

Potassium channelBiophysicsChemistryKcsA potassium channelMembrane potentialTransmembrane domainSelectivityIon channelBiochemistryBiologyAmino acidReceptorCatalysisIon channel regulation and functionIon Channels and ReceptorsIon Transport and Channel Regulation
A lower X-gate in TASK channels traps inhibitors within the vestibule | Litcius