Repurposing of glycine transport inhibitors for the treatment of erythropoietic protoporphyria
François Halloy, Pavithra S. Iyer, Alice Ghidini, Veronika Lysenko, Jasmin Barman‐Aksözen, Chia-Pei Grubenmann, Jessica Jucker, Nicole Wildner-Verhey van Wijk, Marc‐David Ruepp, Elisabeth I. Minder, Anna-Elisabeth Minder, Xiaoye Schneider‐Yin, Alexandre Theocharides, Daniel Schümperli, Jonathan Hall
Topics & Concepts
FerrochelataseErythropoietic protoporphyriaProtoporphyrin IXGlycineOxidative stressChemistryHemeProtoporphyrinPorphyriaK562 cellsBiochemistryEnzymePharmacologyCancer researchBiologyCellAmino acidPhotodynamic therapyEndocrinologyPorphyrinOrganic chemistryPorphyrin Metabolism and DisordersNeonatal Health and BiochemistryHeme Oxygenase-1 and Carbon Monoxide