Secondary Metabolites from Marine <i>Micromonospora</i>: Chemistry and Bioactivities
Sisi Qi, Min Gui, Huanhuan Li, Chunbo Yu, Hongji Li, Zheling Zeng, Peng Sun
Abstract
Marine Micromonospora was revealed to be a rather untapped and a rich source of chemically diverse and unique bioactive natural products. This review is aimed to make a comprehensive survey of secondary metabolites that were derived from marine Micromonospora including chemical diversity and biological activities. A total of 116 compounds from 41 marine Micromonospora species have been reported, covering the literatures from 1997 to 2019. These compounds contain several structural classes such as polyketides (PKS), nonribosomal peptides (NRPS), PKS-NRPS hybrids, terpenes and others, and they present cytotoxic, antibacterial, antiparasitic, chemopreventive or antioxidant activities.