Effect of Antibiotic Use Within First 48 Hours of Life on the Preterm Infant Microbiome
Christina S. Kim, Nicole Grady, Matthew Derrick, Yueyue Yu, Kaitlyn Oliphant, Jing Lü, Erika C. Claud
Abstract
This randomized clinical trial investigates whether withholding the standard 48 hours of intravenous empirical antibiotics immediately after birth in preterm infants protects the developing microbiome and improves clinical outcomes.
Topics & Concepts
MedicineMicrobiomeAntibioticsRandomized controlled trialPediatricsClinical trialIntensive care medicineInternal medicineBioinformaticsMicrobiologyBiologyInfant Development and Preterm CareInfant Nutrition and HealthUrinary Tract Infections Management