Sclerostin antibody increases trabecular bone and bone mechanical properties by increasing osteoblast activity damaged by whole-body irradiation in mice
Samantha Costa, Heather Fairfield, Mariah Farrell, Connor Murphy, Ashley N. Soucy, Calvin Vary, Gill Holdsworth, Michaela R. Reagan
Topics & Concepts
SclerostinOsteoblastCortical boneBone resorptionInternal medicineBone marrowEndocrinologyChemistryIrradiationHindlimbMedicinePathologyIn vitroPhysicsGeneWnt signaling pathwayBiochemistryNuclear physicsBone health and treatmentsBone health and osteoporosis researchBone Metabolism and Diseases