Revealing the Characteristics of Glucose- and Lactate-Based Chain Elongation for Caproate Production by <i>Caproicibacterium lactatifermentans</i> through Transcriptomic, Bioenergetic, and Regulatory Analyses
Huilin Wang, Weicheng Zhou, Jiangjing Gao, Cong Ren, Yan Xu
Abstract
to different carbon sources were unknown. Here, the molecular mechanisms of biomass synthesis supported by glucose utilization and the cell survival supported by lactate utilization were revealed. A novel insight into the regulatory machinery in which glucose negatively regulates lactate utilization was proposed. This study provides a valuable basis to control and optimize caproate production, which will contribute to achieving a circular economy and environmental sustainability.
Topics & Concepts
MaltoseFermentationBiochemistryChemistryTranscriptomeFood scienceBiologyGeneGene expressionEnzymeEnzyme Production and CharacterizationBiofuel production and bioconversionMicrobial Metabolic Engineering and Bioproduction