Mechanism of the Aryl–F Bond-Forming Step from Bi(V) Fluorides
Oriol Planas, Vytautas Pečiukėnas, Markus Leutzsch, Nils Nöthling, Dimitrios A. Pantazis, Josep Cornellà
Abstract
anion, reminiscent of the Balz-Schiemann reaction. The knowledge gathered throughout the investigation permitted a rational assessment of the key parameters of several ligands, identifying the simple sulfone-based ligand family as an improved system for the stoichiometric and catalytic fluorination of arylboronic acid derivatives.
Topics & Concepts
ChemistryArylMechanism (biology)Medicinal chemistryStereochemistryOrganic chemistryAlkylPhilosophyEpistemologyFluorine in Organic ChemistryInorganic Fluorides and Related CompoundsCatalytic Cross-Coupling Reactions