Litcius/Paper detail

Bifunctional small molecules that mediate the degradation of extracellular proteins

David Caianiello, Mengwen Zhang, Jason D. Ray, Rebecca Howell, Jake C. Swartzel, Emily Branham, Egor Chirkin, Venkata R. Sabbasani, Angela Gong, D McDonald, Viswanathan Muthusamy, David A. Spiegel

2021Nature Chemical Biology231 citationsDOI

Topics & Concepts

Asialoglycoprotein receptorExtracellularCell biologyProtein degradationProteasomeBiochemistryChemistryBiologyIn vitroHepatocyteProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysEndoplasmic Reticulum Stress and Disease