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Identification of the anti-fungal drug fenticonazole nitrate as a novel PPARγ-modulating ligand with good therapeutic index: Structure-based screening and biological validation

Lei Ma, Yuling Lian, Junyuan Tang, Fangyuan Chen, Hui Gao, Zhi Zhou, Ning Hou, Wei Yi

2021Pharmacological Research18 citationsDOI

Topics & Concepts

RosiglitazonePharmacologyChemistryPeroxisome proliferator-activated receptorDrugAdipogenesisComputational biologyBiochemistryIn vitroReceptorBiologyPeroxisome Proliferator-Activated ReceptorsMetabolism, Diabetes, and CancerCancer, Lipids, and Metabolism
Identification of the anti-fungal drug fenticonazole nitrate as a novel PPARγ-modulating ligand with good therapeutic index: Structure-based screening and biological validation | Litcius