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Use of Isopropyl Alcohol as a Reductant for Catalytic Dehydoxylative Dimerization of Benzylic Alcohols Utilizing Ti−O Bond Photohomolysis

Keiichi Sumiyama, Naoyuki Toriumi, Nobuharu Iwasawa

2021European Journal of Organic Chemistry29 citationsDOI

Abstract

Abstract Photohomolysis of Ti−O bonds is utilized in photocatalytic generation of titanium(III) species for dehydroxylative dimerization of benzylic alcohols under UV‐light irradiation by using isopropyl alcohol (IPA) as a stoichiometric reductant. In this reaction, IPA works not as a single‐electron donor as in the photo‐redox catalyzed reactions but as an H‐atom‐donor. The reaction also proceeds under visible‐light irradiation in the presence of thioglycolic acid as a ligand.

Topics & Concepts

ChemistryIsopropyl alcoholPhotocatalysisIsopropylCatalysisPhotochemistryAlcoholAlcohol oxidationThioglycolic acidRedoxLigand (biochemistry)StoichiometryIrradiationMedicinal chemistryOrganic chemistryBiochemistryReceptorNuclear physicsPhysicsRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsOxidative Organic Chemistry Reactions
Use of Isopropyl Alcohol as a Reductant for Catalytic Dehydoxylative Dimerization of Benzylic Alcohols Utilizing Ti−O Bond Photohomolysis | Litcius