Development of an MIP based electrochemical sensor for TGF-β1 detection and its application in liquid biopsy
Giulia Siciliano, Maria Serena Chiriacò, Francesco Ferrara, Antonio Turco, L. Velardi, M.A. Signore, Marco Esposito, Giuseppe Gigli, Elisabetta Primiceri
Abstract
and affinity and selectivity to TGF-β1 also in the presence of interfering molecules. The sensor was used also for the detection of target molecules in spiked saliva samples with good recovery results suggesting the possibility of the use of the proposed system for large scale fast screening in oral cancer diagnosis.
Topics & Concepts
ElectrochemistryElectrochemical gas sensorCharacterization (materials science)NanotechnologyChemistryComputer scienceChromatographyMaterials scienceElectrodePhysical chemistryAdvanced biosensing and bioanalysis techniquesAnalytical Chemistry and SensorsBiosensors and Analytical Detection