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Continuous Flow Technology as an Enabler for Innovative Transformations Exploiting Carbenes, Nitrenes, and Benzynes

Kian Donnelly, Marcus Baumann

2022The Journal of Organic Chemistry22 citationsDOIOpen Access PDF

Abstract

Miniaturization offered by microreactors provides for superb reaction control as well as excellent heat and mass transfer. By performing chemical reactions in microreactors or tubular systems under continuous flow conditions, increased safety can be harnessed which allows exploitation of these technologies for the generation and immediate consumption of high-energy intermediates. This Synopsis demonstrates the use of flow technology to effectively exploit benzynes, carbenes, and nitrenes in synthetic chemistry programs.

Topics & Concepts

ChemistryMicroreactorMiniaturizationNitreneFlow chemistryNanotechnologyContinuous flowAryneProcess engineeringBiochemical engineeringOrganic chemistryEngineeringCatalysisMaterials scienceInnovative Microfluidic and Catalytic Techniques InnovationAsymmetric Hydrogenation and CatalysisCatalytic Cross-Coupling Reactions
Continuous Flow Technology as an Enabler for Innovative Transformations Exploiting Carbenes, Nitrenes, and Benzynes | Litcius