Polyamine Metabolism and Functions: Key Roles in Cellular Health and Disease
Marianna Nicoletta Rossi, Manuela Cervelli
Abstract
The polyamines putrescine, spermidine, and spermine are polycations ubiquitously present in cells, where they exert pleiotropic functions in cellular mechanisms like proliferation, protein synthesis (through the hypusination of the transcription factor EIF5a), redox balance, autophagy, and different forms of cell death [...].
Topics & Concepts
SpermidineAutophagyPutrescineSperminePolyamineCellular metabolismCell biologyTranscription factorMetabolismProgrammed cell deathCell growthCellChemistryBiologyBiochemistryEnzymeApoptosisGenePolyamine Metabolism and ApplicationsCannabis and Cannabinoid ResearchAmino Acid Enzymes and Metabolism