Cyclosporin A improves the hyperosmotic response in an experimental dry eye model by inhibiting the HMGB1/TLR4/NF-κB signaling pathway
Jiachao Shen, Yan Liang, Zhaojing Bi, Xin Yin, Chen Chen, Xinmei Zhao, Shujun Liu, Yuanbin Li
Topics & Concepts
HMGB1Osmotic concentrationTLR4Signal transductionNF-κBIn vivoReceptorStimulationInflammationCell biologyTranscription factorPharmacologyChemistryMedicineCancer researchBiologyImmunologyBiochemistryInternal medicineGeneBiotechnologyOcular Surface and Contact LensAdvanced Glycation End Products researchCorneal Surgery and Treatments