Total synthesis of dimeric <i>Securinega</i> alkaloids (−)-flueggenines D and I
Sangbin Jeon, Jinwoo Lee, Sangbin Park, Sunkyu Han
Abstract
The first total synthesis of dimeric securinega alkaloids (−)-flueggenines D and I was completed by a dimerization strategy that involves Stille reaction and stereoselective conjugate reduction.
Topics & Concepts
Stille reactionStereoselectivityChemistryConjugateTotal synthesisStereochemistryCombinatorial chemistryOrganic chemistryCatalysisMathematical analysisMathematicsPhytochemistry and Bioactivity StudiesAlkaloids: synthesis and pharmacologyChemical synthesis and alkaloids