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Fisetin-induced PTEN expression reverses cellular senescence by inhibiting the mTORC2-Akt Ser473 phosphorylation pathway in vascular smooth muscle cells

Seul Gi Kim, Jin Young Sung, Jae-Ryong Kim, Hyoung Chul Choi

2021Experimental Gerontology28 citationsDOI

Topics & Concepts

mTORC2PTENFisetinPI3K/AKT/mTOR pathwaymTORC1Cell biologyProtein kinase BSenescenceBiologyCancer researchSignal transductionBiochemistryFlavonoidAntioxidantPI3K/AKT/mTOR signaling in cancerNeutrophil, Myeloperoxidase and Oxidative Mechanismsmelanin and skin pigmentation
Fisetin-induced PTEN expression reverses cellular senescence by inhibiting the mTORC2-Akt Ser473 phosphorylation pathway in vascular smooth muscle cells | Litcius