Polymeric versus lipid nanocapsules for miconazole nitrate enhanced topical delivery: <i>in vitro</i> and <i>ex vivo</i> evaluation
Rania S. Abdel-Rashid, Doaa A. Helal, Ahmed Adel Alaa-Eldin, Raghda Abdel-monem
Abstract
). The antifungal activity of the PNCs was high 19.07 mm compared to 11.4 mm for LNCs. In conclusion, PNCs may have an advantage over LNCs by offering dual action for both superficial and deep fungal infections.
Topics & Concepts
NanocapsulesPermeationEx vivoZeta potentialMaterials scienceIn vivoDrug deliveryMiconazole NitrateParticle sizeMiconazoleBioavailabilityChemical engineeringChemistryIn vitroNanoparticleNanotechnologyBiochemistryPharmacologyAntifungalMembraneBiotechnologyEngineeringMedicineBiologyDermatologyNail Diseases and TreatmentsAdvanced Drug Delivery SystemsAntifungal resistance and susceptibility