The Management of Brain Metastases—Systematic Review of Neurosurgical Aspects
Martin Proescholdt, Petra Schödel, Christian Doenitz, Tobias Pukrop, Julius Höhne, Nils Ole Schmidt, Karl-Michael Schebesch
Abstract
The multidisciplinary management of patients with brain metastases (BM) consists of surgical resection, different radiation treatment modalities, cytotoxic chemotherapy, and targeted molecular treatment. This review presents the current state of neurosurgical technology applied to achieve maximal resection with minimal morbidity as a treatment paradigm in patients with BM. In addition, we discuss the contribution of neurosurgical resection on functional outcome, advanced systemic treatment strategies, and enhanced understanding of the tumor biology.
Topics & Concepts
MedicineSurgical resectionModalitiesResectionRadiation therapyTreatment modalityChemotherapyNeurosurgeryRadiologySurgerySocial scienceSociologyBrain Metastases and TreatmentGlioma Diagnosis and TreatmentLung Cancer Research Studies