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HPLC method to resolve, identify and quantify guanine nucleotides bound to recombinant ras GTPase

Jonathan P. Hannan, G. Hayden Swisher, Justin G. Martyr, Nicholas J. Cordaro, Annette H. Erbse, Joseph J. Falke

2021Analytical Biochemistry12 citationsDOIOpen Access PDF

Topics & Concepts

NucleotideGTPaseGTP'GuanineRas superfamilyBiochemistryGuanosine triphosphateGuanine nucleotide exchange factorGuanosine diphosphateChemistryBiologyMutantEnzymeGeneProtein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancerCellular transport and secretion
HPLC method to resolve, identify and quantify guanine nucleotides bound to recombinant ras GTPase | Litcius