Hydroxyl Radical Production by Air Pollutants in Epithelial Lining Fluid Governed by Interconversion and Scavenging of Reactive Oxygen Species
Steven Lelieveld, Jake Wilson, Eleni Dovrou, Ashmi Mishra, Pascale S. J. Lakey, Manabu Shiraiwa, Ulrich Pöschl, Thomas Berkemeier
Abstract
fate, causing a strong nonlinear increase in OH production. This shift in ROS chemistry and the enhanced OH production provide a tentative mechanistic explanation for how the inhalation of PM2.5 induces oxidative stress and adverse health effects.
Topics & Concepts
Reactive oxygen speciesChemistryOxidative stressHydroxyl radicalHydrogen peroxideOzoneEnvironmental chemistryPollutantRadicalReactive nitrogen speciesScavengerBiochemistryOrganic chemistryAir Quality and Health ImpactsClimate Change and Health ImpactsAir Quality Monitoring and Forecasting