A ROS-responsive biomimetic nano-platform for enhanced chemo-photodynamic-immunotherapy efficacy
Huixian Yan, Yanan Zhang, Yu Zhang, Yingying Li, Xinru Kong, Dongzhu Liu, Jin Li, Yanwei Xi, Jianbo Ji, Lei Ye, Guangxi Zhai
Abstract
immune response induced an increase in positive immune responders, suppressed negative immune suppressors, and established an inflammatory tumor immune environment, leading to excellent results in tumor suppression and lung metastasis. In conclusion, this novel multifunctional PCDD nanoparticle is a promising platform for tumor combined chemotherapy, photodynamic therapy (PDT) and immunotherapy.
Topics & Concepts
Photodynamic therapyImmunotherapyCancer researchIn vivoMetastasisImmune systemDrug deliveryTumor microenvironmentMicrovesiclesIn vitroChemistryMedicineImmunologyCancerBiologyInternal medicineBiochemistryBiotechnologyOrganic chemistryGenemicroRNANanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesImmunotherapy and Immune Responses