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New contributions to the drug profile of TNFα inhibitor SPD304: Affinity, selectivity and ADMET considerations

Aïda Mascret, Hadley Mouhsine, Ghada Attia, Damien Cabrera, Mohamed Benchekroun, Patrick Gizzi, Chouki Zerrouki, Najla Fourati, Jean‐François Zagury, Maité Sylla‐Iyarreta Veitía, Marc Port

2021European Journal of Pharmacology17 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryTumor necrosis factor alphaIn silicoPharmacologyReceptorMechanism of actionCytotoxicityDrugIn vitroBiochemistryBiologyImmunologyGeneComputational Drug Discovery MethodsCytokine Signaling Pathways and InteractionsMonoclonal and Polyclonal Antibodies Research
New contributions to the drug profile of TNFα inhibitor SPD304: Affinity, selectivity and ADMET considerations | Litcius