Genome-wide admixture and association analysis identifies African ancestry–specific risk loci of eosinophilic esophagitis in African Americans
Yadu Gautam, Julie M. Caldwell, Leah C. Kottyan, Mirna Chehade, Evan S. Dellon, Marc E. Rothenberg, Tesfaye B. Mersha, Joshua B. Wechsler, Carla Davis, Glenn T. Furuta, Paneez Khoury, Seema S. Aceves, Sandeep Kumar Gupta, Jonathan M. Spergel, John Leung, Paul Menard‐Katcher, Gary W. Falk, Ikuo Hirano, Nirmala Gonsalves, Kathryn A. Peterson
Topics & Concepts
Genome-wide association studyImputation (statistics)Eosinophilic esophagitisBiologyGeneticsGenetic association1000 Genomes ProjectPopulationAncestry-informative markerPopulation stratificationGenotypeDiseaseSingle-nucleotide polymorphismMedicineInternal medicineGeneEnvironmental healthMachine learningMissing dataComputer scienceEosinophilic EsophagitisEosinophilic Disorders and SyndromesIL-33, ST2, and ILC Pathways