Origins of SARS‐CoV‐1 and SARS‐CoV‐2 are often poorly explored in leading publications
John W. Wenzel
Abstract
In the rush to understand the coronaviruses that threaten human health, authors of many prominent papers have not performed phylogenetic analyses to the standard of the field today. Errors include faulty placement of the root of the phylogeny, outdated methods of reconstruction, poor taxon sampling, inappropriate emphasis on selected functional elements, and inadequate consideration of ambiguity. As a result, certain conclusions regarding the origin of human infections are not supported soundly or are wrong.
Topics & Concepts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)AmbiguityPhylogenetic treeCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakTaxonBiologyEvolutionary biologyVirologyHistoryGeographyData scienceDiseaseEcologyInfectious disease (medical specialty)MedicineComputer sciencePathologyOutbreakGeneticsGeneProgramming languageSARS-CoV-2 and COVID-19 ResearchZoonotic diseases and public healthCOVID-19 epidemiological studies