Loss of Function in the Neurodevelopmental Disease and Schizophrenia-Associated Gene CYFIP1 in Human Microglia-like Cells Supports a Functional Role in Synaptic Engulfment
Steven D. Sheridan, Joy E. Horng, Hana Yeh, Liam McCrea, Jennifer Wang, Ting Fu, Roy H. Perlis
Topics & Concepts
MicrogliaSynaptic pruningPhenotypeNeuroscienceBiologyCell typeKnockout mouseGene knockoutSynaptic vesicleCell biologyGeneCellImmunologyGeneticsVesicleInflammationMembraneNeuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanismsTryptophan and brain disorders