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Spray drying of API nanosuspensions: Importance of drying temperature, type and content of matrix former and particle size for successful formulation and process development

Stefan Czyz, Martin Wewers, Jan Henrik Finke, Arno Kwade, Bernard Van Eerdenbrugh, Michael Juhnke, Heike Bunjes

2020European Journal of Pharmaceutics and Biopharmaceutics22 citationsDOI

Topics & Concepts

Spray dryingParticle sizeFreeze-dryingMatrix (chemical analysis)NanoparticleActive ingredientChromatographyExtrusionCritical quality attributesChemistryIngredientParticle (ecology)Materials scienceChemical engineeringNanotechnologyComposite materialFood scienceBioinformaticsEngineeringPhysical chemistryBiologyOceanographyGeologyMicroencapsulation and Drying ProcessesDrug Solubulity and Delivery SystemsAdvanced Drug Delivery Systems
Spray drying of API nanosuspensions: Importance of drying temperature, type and content of matrix former and particle size for successful formulation and process development | Litcius