Targeted isolation of two disesquiterpenoid macrocephadiolides A and B from <i>Ainsliaea macrocephala</i> using a molecular networking-based dereplication strategy
Yong-Mei Ren, Shuaizhen Zhou, Tian Zhang, Meijia Qian, Rui Zhang, Sheng Yao, Hong Zhu, Chunping Tang, Ligen Lin, Yang Ye
Abstract
Two novel dimeric sesquiterpenoids with potent anti-inflammatory activity were characterized from <italic>Ainsliaea macrocephala</italic> through a molecular networking-based dereplication strategy.
Topics & Concepts
ChemistryIsolation (microbiology)Traditional medicineComputational biologyStereochemistryBioinformaticsBiologyMedicinePhytochemistry and Biological ActivitiesNatural product bioactivities and synthesisPlant-derived Lignans Synthesis and Bioactivity