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Design, synthesis, in silico and biological evaluation of new indole based oxadiazole derivatives targeting estrogen receptor alpha

Kamalpreet Kaur, Harkomal Verma, Prabhakar Gangwar, Kailash Jangid, Monisha Dhiman, Vinod Kumar, Vikas Jaitak

2024Bioorganic Chemistry18 citationsDOI

Topics & Concepts

ChemistryTransactivationEstrogen receptorEstrogen receptor alphaIndole testOxadiazoleIC50In silicoStereochemistryWestern blotDocking (animal)In vitroBiochemistryCancerBreast cancerTranscription factorGeneInternal medicineOrganic chemistryMedicineNursingSynthesis and biological activityComputational Drug Discovery MethodsSynthesis of Tetrazole Derivatives
Design, synthesis, in silico and biological evaluation of new indole based oxadiazole derivatives targeting estrogen receptor alpha | Litcius