A cooperative Pd/Co catalysis system for the asymmetric (4+2) cycloaddition of vinyl benzoxazinones with <i>N</i>-acylpyrazoles
Wei Xiong, Xuan‐Feng Jiang, Mao‐Mao Zhang, Wen‐Jing Xiao, Liang‐Qiu Lu
Abstract
-configured stereocenters were produced in high yields and enantio- and diastereoselectivities. The pyrazole directing group can be easily converted into many other functional groups, thus demonstrating the flexibility of the present methodology.
Topics & Concepts
CycloadditionStereocenterCatalysisChemistryEnantioselective synthesisCombinatorial chemistryFlexibility (engineering)Organic chemistryMathematicsStatisticsCyclopropane Reaction MechanismsSynthesis and Catalytic ReactionsCatalytic Alkyne Reactions