Enzyme-active liquid coacervate microdroplets as artificial membraneless organelles for intracellular ROS scavenging
Yufeng Chen, Min Yuan, Yanwen Zhang, Shaohong Zhou, Kemin Wang, Zhenjun Wu, Jianbo Liu
Abstract
provides a novel approach for designing artificial membraneless organelles in living cells. The strategy of using artificial organelle-mediated enzymatic reactions to supplement cellular dysfunctions can be exploited for their further biomedical applications.
Topics & Concepts
CoacervateChemistryIntracellularScavengingEnzymeOrganelleBiochemistryBiophysicsAntioxidantBiologyPer- and polyfluoroalkyl substances researchSupramolecular Self-Assembly in MaterialsLipid Membrane Structure and Behavior