An in-silico evaluation of dietary components for structural inhibition of SARS-Cov-2 main protease
Anand Kumar Pandey, Shalja Verma
Abstract
enzyme. They interacted with excellent efficiency with the chief active site residue Cys145 and thus seem to possess the remarkable potential to act as drug candidates for the treatment of Covid-19. Such dietary compounds can be easily administered orally with least toxicity related concern and thus yell for urgent exhaustive research to develop into efficient therapies.Communicated by Ramaswamy H. Sarma.
Topics & Concepts
In silicoProteasePharmacologySmall moleculeComputational biologyDocking (animal)Drug discoveryChemistryRNA-dependent RNA polymeraseEnzymeBiochemistryBiologyMedicineNursingGenePolymeraseComputational Drug Discovery MethodsPhytochemicals and Antioxidant ActivitiesCholinesterase and Neurodegenerative Diseases