IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy
Ting Zhou, William Damsky, Orr-El Weizman, Meaghan K. McGeary, K. Patricia Hartmann, Connor Rosen, Suzanne Fischer, Ruaidhrí Jackson, Richard A. Flavell, Jun Wang, Miguel F. Sanmamed, Marcus Bosenberg, Aaron M. Ring
Topics & Concepts
ImmunotherapyCD8BiologyCytokineImmunologyCancer immunotherapyCancer researchImmune systemCytotoxic T cellInterleukin 15InterleukinIn vitroBiochemistryInflammasome and immune disordersImmune Cell Function and InteractionCancer Immunotherapy and Biomarkers