Itaconate and leptin affecting PPARγ in M2 macrophages: A potential link to early-onset colorectal cancer
Katharina M. Scheurlen, Dylan L. Snook, Mary Nancy Walter, Cheyenne N. Cook, Casey Fiechter, Jianmin Pan, Robert J. Beal, Susan Galandiuk
Topics & Concepts
Downregulation and upregulationMedicineLeptinInternal medicineColorectal cancerPeroxisome proliferator-activated receptorEndocrinologyCytokineReceptorTumor necrosis factor alphaCancerCancer researchObesityBiologyBiochemistryGenePeroxisome Proliferator-Activated ReceptorsImmune cells in cancerAdipokines, Inflammation, and Metabolic Diseases