NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly
Feng He, Laura Antonucci, Shinichiro Yamachika, Zechuan Zhang, Koji Taniguchi, Atsushi Umemura, Georgia Hatzivassiliou, Merone Roose‐Girma, Miguel Reina‐Campos, Ángeles Durán, María T. Díaz‐Meco, Jorge Moscat, Beicheng Sun, Michael Karin
Topics & Concepts
Downstream (manufacturing)Cell biologyProtein kinase BGeneSignal transductionCancer researchGrowth factorBiologyChemistryGeneticsBusinessReceptorMarketingLiver Diseases and ImmunityLiver Disease Diagnosis and TreatmentLiver physiology and pathology