Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism
Jiangxin Liu, Xing‐De Wu, Wenyan Li, Zaifeng Yuan, Kun Yang, Qin‐Shi Zhao
Topics & Concepts
ChemistryHeLaHsp90Mechanism of actionApoptosisMechanism (biology)Cell cycle checkpointBiochemistryCancer cellCellCell cycleCancerHeat shock proteinIn vitroBiologyGeneticsPhilosophyEpistemologyGeneBiological Activity of Diterpenoids and BiflavonoidsNatural product bioactivities and synthesisPlant biochemistry and biosynthesis