Litcius/Paper detail

Plastic-based lateral flow immunoassay device for electrochemical detection of NT-proBNP

Nikhil Raj, Richard M. Crooks

2022The Analyst20 citationsDOIOpen Access PDF

Abstract

Flow device is capable of on-chip storage, resolvation, and conjugate formation of both the MC and NT-proBNP composites. Third, electrochemical detection can be conducted on analytes suspended in serum by rinsing the electrodes with a wash buffer. Finally, and perhaps most significantly, the assay is quantitative and has a detection limit for NT-proBNP in the high picomolar range when the necessary reagents are stored on the device in a dry form.

Topics & Concepts

ImmunoassayFlow (mathematics)Materials scienceMechanicsMedicinePhysicsAntibodyImmunologyAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical DetectionAnalytical Chemistry and Sensors