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Maternal supplementation with glycerol monolaurate improves the intestinal health of suckling piglets by inhibiting the NF-κB/MAPK pathways and improving oxidative stability

Hao Zhao, Min Tian, Liang Xiong, Tongbin Lin, Shuchang Zhang, Shuchang Zhang, Xianhuai Yue, Xinghong Liu, Fang Chen, Shihai Zhang, Shihai Zhang, Wutai Guan

2023Food & Function17 citationsDOI

Abstract

. In summary, a sow diet supplemented with GML enhanced the offspring's intestinal oxidative stability and barrier function and attenuated the offspring's intestinal inflammatory response, possibly by suppressing the activation of the NF-κB/MAPK pathways.

Topics & Concepts

OffspringMAPK/ERK pathwayOxidative stressNF-κBOxidative phosphorylationHomeostasisPharmacologyBiologyChemistryEndocrinologySignal transductionInternal medicineMedicineCell biologyBiochemistryPregnancyGeneticsAnimal Nutrition and PhysiologyReproductive Physiology in LivestockEffects of Environmental Stressors on Livestock